HSP40: Database IDs
ICC staining of Hsp47 in heat shocked HeLa cells using Anti-Hsp47 (clone: 1C4-1A6) and a FITC secondary (green: cytoplasm; blue: DAPI nuclear stain)
Table 2 provides an overview of UniProt and Gene IDs of various pro- and eukaryotic DNAJs/HSP40s.
Table 1: Human and mouse orthologs of Hsp40 (DnaJB1)
| Human | Mouse | |
| Entrez Gene | 3337 | 81489 |
| Ensembl | ENSG00000132002 | ENSMUSG00000005483 |
| UniProt | P25685 | Q9QYJ3 |
| Reference sequence (mRNA) | NM_006145.2 | NM_018808.2 |
| Reference sequence (Protein) | NP_006136.1 | NP_061278.1 |
| Gene locus | Chr19:14,514,770-14,529,770 | Chr 8:83,608,175-83,611,902 |
| Pfam | PF00226, PF00684, PF01556 | PF00226, PF00684, PF01556 |
Table 2: HSP40s/DNAJs of various pro- and eukaryotic organisms
| Gene | Protein | Aliases | UniProt ID | Gene ID |
| M.mazei | ||||
| Type 1 (subfamily A) | ||||
| dnaJ | DnaJ | Chaperone protein DnaJ, Hsp40, NP_634528.1 | P0CW07 | 1480846 |
| M.acetivorans | ||||
| Type 1 (subfamily A) | ||||
| dnaJ | DnaJ | Chaperone protein DnaJ, Hsp40, NP_616413.1 | Q8TQR1 | 1473367 |
| E. coli | ||||
| Type 1 (subfamily A) | ||||
| dnaJ | DnaJ | Hsp40, HspJ, HSP40, GroP | P08622 | 944753 |
| Type 2 (subfamily B) | ||||
| cbpA | CbpA | Curved DNA-binding protein, YP_489273.1 | P36659 | 12932265 |
| Type 3 (subfamily C) | ||||
| djlA | DjlA | DnaJ-like protein | P31680 | 12932622 |
| djlB | DjlB | J domain-containing protein DjlB, YP_488937.1 | P77381 | 12930913 |
| djlC | DjlC | J domain-containing protein DjlC, Hsc56 co-chaperone of HscC, YP_488940.1 | P77359 | 12932384 |
| hscB | HscB | Hsc20, DnaJ-like molecular chaperone-specific for IscU | P0A6L9 | 12934043 |
| S.cerevisiae | ||||
| Type 1 (subfamily A) | ||||
| YDJ1 | Ydj1 | Mas5, Mab3, type I Hsp40 co-chaperone YDJ1 | P25491 | 855661 |
| XDJ1 | Xdj1 | DnaJ homolog protein XDJ1, NP_013191.1 | P39102 | 850779 |
| APJ1 | Apj1 | J domain-containing protein APJ1, Ynl077w, NP_014322.1 | P53940 | 855647 |
| MDJ1 | Mdj1 | DnaJ homolog 1, mitochondrial; NP_116638.1 | P35191 | 850530 |
| SCJ1 | Scj1 | DnaJ-related protein SCJ1, NP_013941.2 | P25303 | 855254 |
| Type 2 (subfamily B) | ||||
| SIS1 | Sis1 | SIS1, Sis-1, NP_014391.1 | P25294 | 855725 |
| DJP1 | Djp1 | DnaJ-like protein 1, peroxisome assembly protein 22 (Pas22), Ics1, NP_012269.1 | P40564 | 854820 |
| CAJ1 | Caj1 | CAJ1, NP_010967.3 | P39101 | 856772 |
| HLJ1 | Hlj1 | NP_013884.1, HLJ1 | P48353 | 855196 |
| Type 3 (subfamily C) | ||||
| CWC23 | Cwc23 | Pre-mRNA-splicing factor CWC23, NP_011387.2, complexed with CEF1 protein 23 | P52868 | 852749 |
| ERJ5 | Erj5 | ER-localized J domain-containing protein 5, NP_116699.3 | P43613 | 850602 |
| SWA2 | Swa2 | Auxilin-like clathrin uncoating factor SWA2, bud site selection protein 24, synthetic lethal with ARF1 protein 2, NP_010606.1 | Q06677 | 851918 |
| SEC63 | Sec63 | Protein translocation protein SEC63, Sec62/63 complex 73 kDa subunit, Ptl1, Npl1, NP_014897.1 | P14906 | 854428 |
| PAM18 | Pam18 | Mitochondrial import inner membrane translocase subunit Tim14, NP_013108.1 | Q07914 | 850694 |
| MDJ2 | Mdj2 | Mitochondrial DnaJ homolog 2, NP_014071.1 | P42834 | 855388 |
| JAC1 | Jac1 | J-type co-chaperone JAC1, mitochondrial; J-type accessory chaperone 1, NP_011497.1 | P53193 | 852866 |
| JEM1 | Jem1 | DnaJ-like protein of the ER membrane 1, Kar-8, NP_012462.3 | P40358 | 853372 |
| JID1 | Jid1 | J domain-containing protein 1, NP_015386.1 | Q12350 | 856174 |
| JJJ1 | Jjj1 | J protein JJJ1, NP_014172.1 | P53863 | 855495 |
| JJJ2 | Jjj2 | J proptein JJJ2, NP_012373.2 | P46997 | 853277 |
| JJJ3 | Jjj3 | Diphthamide biosynthesis protein 4, Dph4, NP_012631.3 | P47138 | 853560 |
| ZUO1 | Zuo1 | Zuotin, DnaJ-related protein ZUO1, heat shock protein 40 homolog ZUO1, ribosome-associated complex subunit ZUO1, NP_011801.1 | P32527 | 853202 |
| J-like | ||||
| JLP1 | Jlp1 | DnaJ-like protein, Jlp1p, NP_013043.1, alpha-ketoglutarate-dependent sulfonate dioxygenase | A7A0K3Q12358 | 850669 |
| JLP2 | Jlp2 | DnaJ-like protein 2, Jlp2p, NP_013851.1 | P40206 | 855162 |
| PAM16 | Pam16 | Mitochondrial import inner membrane translocase subunit Tim16, presequence translocated-associated motor subunit PAM16, Pam16p, NP_012431.1 | P42949 | 853340 |
| Human | ||||
| Type 1 (subfamily A) | ||||
| DNAJA1 | DnaJA1 | HSDJ, DJ2, human DnaJ protein 2 (hDj-2), Hsj2, HSPF4, Hdj2, DjA1 | P31689 | 3301 |
| DNAJA2 | DnaJA2 | Dnj3, Dn3, HIRA-interacting protein 4, renal carcinoma antigen NY-REN-14, HIRIP4, DjA2 | O60884 | 10294 |
| DNAJA3 | DnaJA3 | Tid-1, hTID-1, hepatocellular carcinoma-associated antigen 57 (HCA57), | Q96EY1 | 9093 |
| DNAJA4 | DnaJA4 | Dj4, Hsj-4, MST104, MSTP104, PRO1472 | Q8WW22 | 55466 |
| Type 2 (subfamily B) | ||||
| DNAJB1 | DnaJB1 | Hsp40, Hdj1, hDj-1, HSPF1, Sis1, RSPH16B | P25685 | 3337 |
| DNAJB2 | DnaJB2 | HSJ1, HSPF3, Hsj1, Dnajb10, mDj8, DSMA5 | P25686 | 3300 |
| DNAJB3 | DnaJB3 | Hcg-3, Hsj-3, Msj1, MSJ-1 | Q8WWF6 | 414061 |
| DNAJB4 | DnaJB4 | human liver DnaJ-like protein, HLJ-1, Hlj1, DjB4, Dnajw | Q9UDY4 | 11080 |
| DNAJB5 | DnaJB5 | Hsc40, Hsp40-2, Hsp40-3 | O75953 | 25822 |
| DNAJB6 | DnaJB6 | DJ4, DnaJ, HHDJ1, HSJ-2, Hsj2, LGMD1D, LGMD1E, Mrj, MSJ-1 | O75190 | 10049 |
| DNAJB7 | DnaJB7 | Dj5, HSC3, mDj5 | Q7Z6W7 | 150353 |
| DNAJB8 | DnaJB8 | DJ6, mDj6 | Q8NHS0 | 165721 |
| DNAJB9 | DnaJB9 | ER-resident protein ERdj4; Mdg1, mDj7 | Q9UBS3 | 4189 |
| DNAJB11 | DnaJB11 | ER-resident protein ERdj3, hDj9, PWP1-interacting protein 4, APOBEC1-binding protein 2 (ABBP-2), HEDJ | Q9UBS4 | 51726 |
| DNAJB12 | DnaJB12 | Dj10, mDj10 | Q9NXW2 | 54788 |
| DNAJB13 | DnaJB13 | testis spermatogenesis apoptosis-related gene 6/3 protein (Tsarg-6/-3), | P59910 | 374407 |
| DNAJB14 | DnaJB14 | ER-resident EGNR9427, PRO34683, FLJ14281 | Q8TBM8 | 79982 |
| Type 3 (subfamily C) | ||||
| DNAJC1 | DnaJC1 | ER-resident protein ERdj1, MTJ1, Htj1, Dnajl1 | Q96KC8 | 64215 |
| DNAJC2 | DnaJC2 | M-phase phosphatase protein 11 (MPHOSPH11), M-phase phosphoprotein 11 (MPP11), zuotin-related factor 1 (Zrf1) | Q99543 | 27000 |
| DNAJC3 | DnaJC3 | ER-resident protein ERdj6, p58, Prkri, protein kinase inhibitor p58 (p58IPK) | Q13217 | 5611 |
| DNAJC4 | DnaJC4 | F2, multiple endocrine neoplasia type 1 candidate protein number 18 | Q9NNZ3 | 3338 |
| DNAJC5 | DnaJC5 | cysteine string protein (Csp) alpha | Q9H3Z4 | 80331 |
| DNAJC5B | DnaJC5B | Csp-beta | Q9UF47 | 85479 |
| DNAJC5G | DnaJC5G | Csp-gamma | Q8N7S2 | 285126 |
| DNAJC6 | DnaJC6 | Auxilin, mKIAA0473, DjC6, Park19 | O75061 | 9829 |
| DNAJC7 | DnaJC7 | Dj11, mDj11, DjC7, tetratricopeptide repeat protein 2 (TPR2, mTpr-2) | Q99615 | 7266 |
| DNAJC8 | DnaJC8 | splicing protein spf31, Hspc315, Hspc331 | O75937 | 22826 |
| DNAJC9 | DnaJC9 | DnaJ protein SB73, HdjC9 | Q8WXX5 | 23234 |
| DNAJC10 | DnaJC10 | ER-resident protein ERdj5, macrothioredoxin (MTHr), JPD1 | Q8IXB1 | 54431 |
| DNAJC11 | DnaJC11 | dJ126A5.1, FLJ10737, RP1-126A5.3 | Q9NVH1 | 55735 |
| DNAJC12 | DnaJC12 | J-domain containing protein 1 (Jdp-1, mJDP1) | Q9UKB3 | 56521 |
| DNAJC13 | DnaJC13 | DNA J-domain containing protein Rme-8 (RME-8), mKIAA0678, Gm1124 | O75165 | 23317 |
| DNAJC14 | DnaJC14 | Hdj3, hDj-3, LYST-interactimng protein 6 (LIP6), dopamine receptor-interacting protein of 78 kDa (DRIP78, Drip-78) | Q6Y2X3 | 85406 |
| DNAJC15 | DnaJC15 | Dnajd1, cell growth-inhibiting gene 22 protein, methylation-controlled J protein(MCJ, Mcj) | Q9Y5T4 | 29103 |
| DNAJC16 | DnaJC16 | mKIAA0962 | Q9Y2G8 | 23341 |
| DNAJC17 | DnaJC17 | DnaJ homolog subfamily C member 17; C87112 | Q9NVM6 | 55192 |
| DNAJC18 | DnaJC18 | DnaJ homolog subfamily C member 18, AU041129 | Q9H819 | 202052 |
| DNAJC19 | DnaJC19 | mitochondrial import inner membrane translocase subunit 14 (TIM14, TIMM14) | Q96DA6 | 131118 |
| DNAJC20 | DnaJC20 | Jac1; Hsc20, HscB | Q8IWL3 | 150274 |
| DNAJC21 | DnaJC21 | Dnaja5, GS3, Jjj1 | Q5F1R6 | 134218 |
| DNAJC22 | DnaJC22 | Wus, wurst homolog (Wurst), AI506245 | Q8N4W6 | 79962 |
| J-like | ||||
| DNAJC23 | DnaJC23 | ER-resident protein ERdj2, Sec63L, Dnajc23 | Q9UGP8 | 11231 |
| DNAJC24 | DnaJC24 | CSL-type zinc finger-containing protein 3 (ZCSL3), JJJ3, diphthamide biosynthesis protein 4 (DPH4, Dph-4), 1700030A21Rik | Q6P3W2 | 120526 |
| DNAJC25 | DnaJC25 | DnaJ homolog subfamily C member 25, bA16L21.2.1, 2010109C08Rik, 2010203O07Rik, | Q9H1X3 | 548645 |
| DNAJC26 | DnaJC26 | Cyclin-G-associated kinase (GAK), auxilin-2 | O14976 | 2580 |
| DNAJC27 | DnaJC27 | RBJ, RabJs, Ras-associated protein 1 (Rap‑1), Rab and DnaJ-domain containing protein | Q9NZQ0 | 51277 |
| DNAJC28 | DnaJC28 | C21orf55; C21orf78, Orf28, oculomedin | Q9NX36 | 54943 |
| DNAJC29 | DnaJC29 | Sacsin (spastic ataxia of Charlevoix-Saguenay), SPAX6, protein phosphatase 1, regulatory subunit 138, KIAA0730 | Q9NZJ4 | 26278 |
| DNAJC30 | DnaJC30 | Williams-Beuren syndrome chromosomal region 18 protein (WBSCR18) | Q96LL9 | 84277 |